Comparison of Thoracic Epidural Bupivacaine with Buprenorphine and Parenteral Ketorolac for Post- Thoracotomy Pain Relief
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چکیده
7,8,9 disorder. Further it requires skill and training, strict asepsis and careful observation of the patient. With parenteral opioids alone, the side effects like respiratory depression are intolerable. Thus, there is a need for choosing drug classes that will overlap for analgesia but not for side effects. Drug class that fits these requirements is that of NSAIDs . The advent of NSAIDs that selectively inhibit COX-2 may reduce COX-1-dependent side effects, opioid requirements and the incidence of chronic pain after surgery. The effectiveness of NSAIDs in alleviating pain and reducing requirements for opioids in the postoperative period
منابع مشابه
Double-blind comparison of intrapleural saline and 0.25% bupivacaine for ipsilateral shoulder pain after thoracotomy in patients receiving thoracic epidural analgesia.
BACKGROUND The aim of this prospective double-blind randomized placebo-controlled study was to investigate the effect of intrapleural bupivacaine on ipsilateral post-thoracotomy shoulder pain in patients receiving thoracic epidural analgesia. METHODS Of the 68 patients recruited to the study, 41(60%) developed ipsilateral shoulder pain within 2 h of surgery. These patients were randomly assig...
متن کاملPost-thoracotomy pain relief with subpleural analgesia or thoracic epidural analgesia: randomized clinical trial.
CONTEXT AND OBJECTIVE Post-thoracotomy pain is a severe and intense pain caused by trauma to ribs, muscles and peripheral nerves. The current study aimed to compare subpleural analgesia (SPA) with thoracic epidural analgesia (TEA) in patients undergoing thoracotomy. DESIGN AND SETTING Randomized study at Ankara Numune Education and Research Hospital, in Turkey. METHODS Thirty patients prese...
متن کاملKetorolac as a component of balanced analgesia after thoracotomy.
Ketorolac 10 mg or 30 mg i.m., 6 hourly or placebo was given to 75 patients who had undergone thoracotomy, in a randomized double-blind study. All subjects were given intercostal nerve blocks with bupivacaine and had access to i.v. patient-controlled morphine. I.m. ketorolac improved the success rate of the analgesic regimen, with fewer patients withdrawing from the study because of inadequate ...
متن کاملComparison of Bolus Bupivacaine, Fentanyl, and Mixture of Bupivacaine with Fentanyl in Thoracic Epidural Analgesia for Upper Abdominal Surgery
Introduction: Thoracic segmental epidural analgesia despite its technical difficulty and time consumption provides better analgesia and has a beneficial effect on the post-operative pulmonary and metabolic function; immunological and stress response. Aims and Objectives: To study the efficacy of fentanyl for pain relief of inpatients after upper abdominal procedures and compare with bupivacaine...
متن کاملContinuous high thoracic epidural administration of morphine with bupivacaine after thoracotomy.
BACKGROUND AND OBJECTIVES The purpose of the study is to determine the ideal concentration of morphine when given with bupivacaine as a continuous high thoracic epidural infusion for postthoracotomy pain. METHODS In a prospective study, 60 patients scheduled for thoracic surgery received a high thoracic epidural catheter. Postoperative analgesia was provided by a continuous epidural infusion ...
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تاریخ انتشار 2015